Obesity - Gallstones - Ursodesoxycholic Acid
Gallstone Formation and Weight Reduction - - Miller K.
|Ursodesoxycholic acid (Ursofalk ®) is effective in prophylaxis of gallstone
formation during weight reduction through diet (Ann
Intern Med 1995; 122:899-905). Gallstone formation is a problem
with rapid loss of weight (references 10-28%). In the
surgery of morbid obesity a gallstone formation is even
observed postoperatively up to 38% (Gastroenterology
1992; 103: 214-221). Numerous centers propagate even a
simultaneous Cholecystectomy for prophylaxis (Am
J Surg 1985; 149: 551-557). A simultaneous Cholecystectomy in
morbid obese patients on the one hand, is through the
entrance, on the other hand through the body abundance
Ursodesoxycholsaeure (Ursofalk ®) is indicated in case of cholestatic disease.
Ursodeoxycholic acid, 600 mg/d, is highly effective in preventing gallstone formation in patients having dietary-induced weight reduction. (Ann Intern Med 1995; 122:899-905).